Published September 21, 1999
by Informa Healthcare .
Written in English
|The Physical Object|
|Number of Pages||262|
ISBN: OCLC Number: Description: viii, pages: illustrations ; 24 cm. Contents: Overview of protein formulation and delivery / James Wright --Chemical considerations in protein and peptide stability / Paul M. Bummer --Physical considerations in protein and peptide stability / Sandy Koppenol --Analytical methods and stability testing of biopharmaceuticals H.A. Schiffter, in Comprehensive Biotechnology (Second Edition), Preservatives. Preservatives will need to be added to a protein formulation if it is filled in multidose vials in order to prevent the growth of bacteria after the first dose withdrawal. Important considerations in regard to choosing a preservative are (1) the current use and route of administration, for example /protein-formulation. Overview of protein formulation and delivery --Chemical and physical consideration in protein and peptide stability --Analytical methods and stability testing of biopharmaceuticals --The importance of a thorough preformulation study --Solution formulation of proteins/peptides --Freeze-drying concepts: the basics --Formulation of proteins for This title is intended to assist pharmaceutical scientists in the development of stable protein formulations during the early stages of the product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage of accelerated stability testing methods and relevant analytica
Protein Formulation and Delivery (Drugs and the Pharmaceutical Sciences Book ) - Kindle edition by McNally, Eugene J., McNally, Eugene, Hastedt, Jayne E.. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Protein Formulation and Delivery (Drugs and the Pharmaceutical Sciences Book ) › Kindle Store › Kindle eBooks › Science & Math. The majority of protein drugs are delivered by the injection route, although there is an increasing interest in alternative delivery routes, e.g., pulmonary. Ready-touse liquid formulations are preferred injectable dosage forms because they are considered easier to manufacture and :// Protein Formulation and Delivery, Second Edition Author: Eugene J. McNally (Editor), Jayne E. Hastedt (Editor) Publisher: Informa Healthcare Publication Date: This handy reference provides insight into the approach used to identify the This title is intended to assist pharmaceutical scientists in the development of stable protein formulations during the early stages of the product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage of accelerated stability testing methods and relevant analytical methods, and an overview of the drug › Books › New, Used & Rental Textbooks › Medicine & Health Sciences.
This chapter highlights the significant advances in brain delivery of peptide and protein drugs made over the past three decades. While many limitations still exist regarding the cerebral delivery of peptide and protein drugs, several strategies show considerable promise for improvement of brain :// Protein formulation and delivery (Book, )  The second edition of Protein Formulation and Delivery presents an updated review of recent research in the formulation and delivery of therapeutic proteins and peptides. The book contains expanded sections about protein characterization and formulation and several new chapters that This handy reference provides insight into the approach used to identify the stability profile of a molecule that comes at the end of the drug registration process, and supplies an in-depth review of the mechanisms and associated causes of protein instability likely to be encountered during drug formulation izes the importance of selecting formulation conditions, excipients Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems, Third Edition provides a comprehensive overview of the field for scientists in industry and academia and for students, while also providing practical information on the challenges facing the formulation and delivery aspects of these unique macromolecules. In /p/book/